Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9404686 | Surgery | 2005 | 9 Pages |
Abstract
Enhanced antitumor activity is achieved in breast cancer by combining celecoxib and Ad-mda7 regardless of HER-2/neu status. This occurs through inhibition of COX-2 expression and down-regulation of Akt. Combining Ad-mda7 with COX-2 inhibition provides a novel method of treatment in breast cancer.
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Authors
Young-Jin MD, Sunil PhD, Tamra MD, Yanna MS, Stephen G. MD, Anthony MD, Kelly K. MD,