Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9404688 | Surgery | 2005 | 11 Pages |
Abstract
To our knowledge, this is the first report demonstrating that melanoma-supported angiogenesis in collagen is more significantly influenced by normal skin-derived fibroblasts than by the intrinsic biology of the melanoma cell type. Interleukin 8, monocyte chemotactic protein-1, and tissue inhibitor of metalloproteinase-2 are implicated as potential paracrine factors regulating this observed effect.
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Authors
Lee J. MD, Haiying MD, Richard J. PhD, Stephen M. MD, Omaida C. MD,