Article ID Journal Published Year Pages File Type
9404829 Surgery 2005 8 Pages PDF
Abstract
Combined SAHA and gemcitabine sensitized NSCLC cells to apoptosis. Potential “proapoptotic” mechanisms for this finding include gemcitabine inhibition of SAHA-induced NF-κB activation and chromatin remodeling mediated by the inhibition of histone deacetylases.
Related Topics
Health Sciences Medicine and Dentistry Surgery
Preview
Suberoylanilide hydroxamic acid combined with gemcitabine enhances apoptosis in non-small cell lung cancer
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