| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9404830 | Surgery | 2005 | 7 Pages |
Abstract
PJ34 preserves renal mitochondrial activity and decreases steady-state levels of NGAL after TAR. TAR did increase markers of fibrinolysis in renal tissue but their increase did not correlate with renal injury or PJ34 treatment. These studies indicate that PJ34 confers protection against TAR and suggest that PARP may represent a novel target for reducing perioperative renal injury.
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Authors
David H. MD, Hassan MD, Mark F. MD, Michael C. MD, Fateh MD, Richard P. MD, Michael T. MD,