| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9406403 | Behavioural Brain Research | 2005 | 8 Pages |
Abstract
Factorial designs offer an efficient approach to study synergistic effects of two treatments. Our graphical technique provides a powerful, intuitive and quantitative explanation of joint treatment effects. Combining thrombolytic therapy with a neuroprotectant yielded a super-additive or additive treatment effect for two preclinical experiments designed to extend the thrombolytic therapeutic window for stroke.
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Authors
Mei Lu, Michael Krams, Li Zhang, Zheng Gang Zhang, Michael Chopp,