Article ID Journal Published Year Pages File Type
9406452 Behavioural Brain Research 2005 5 Pages PDF
Abstract
The behavioral consequences of intermittent, 5 s cold-water swims (15 °C) or confinement were assessed 24 h after stress in a 5 min forced swim test or an instrumental swim escape test (SET). The SET was conducted with temporal and instrumental parameters similar to the shock-motivated shuttle escape test. The tests detected significantly increased immobility in the forced swim test and increased latency to escape in the SET. These results extend previous findings with intermittent swim stress and provide evidence that intermittent swim stress produces behavioral deficits similar to other stress models. This new model may be a useful tool for exploring the physiological mechanisms underlying the stress response.
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