| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9416568 | Brain Research | 2005 | 4 Pages |
Abstract
Recent studies suggest that the gene that encodes brain-derived neurotrophic factor (BDNF) might be linked with vulnerability to alcohol abuse. We have now compared BDNF protein levels in several brain regions between alcohol-naïve alcohol-preferring (P) and -nonpreferring (NP) rats using the enzyme-linked immunosorbent assay (ELISA) procedure. The results showed that BDNF levels in the nucleus accumbens of the P rats were significantly lower than those of the NP rats, suggesting that this innate difference may contribute to the disparate alcohol drinking behavior of the P and NP rats.
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Neuroscience (General)
Authors
Qing-Shan Yan, Mei-Jiang Feng, Shu-E Yan,