| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9416715 | Brain Research | 2005 | 4 Pages |
Abstract
This study aims to explore the effects of a selective 5-HT1B receptor agonist, CGS-12066A, on the neuronal excitability of the rat medial vestibular nuclear neurons. The spontaneous firing rate was decreased, and the membrane potential was hyperpolarized by CGS-12066A. The whole potassium currents were inhibited by CGS-12066A. After the calcium-dependent potassium, currents were blocked, however, CGS-12066A did not inhibit the potassium currents, suggesting that the 5-HT action site is calcium-dependent potassium currents.
Keywords
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Han-Seong Jeong, Myung-Joo Jang, Jong-Seong Park,