| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9416787 | Brain Research | 2005 | 8 Pages |
Abstract
Two week pre-treatment with a high physiological dose of 17β-oestradiol increased infarct volume after permanent MCAO. Although contrary to our original hypothesis, this result demonstrates that oestrogen does have the capacity to promote detrimental actions in the stroke-injured brain. Given the wide use of oestrogen (contraception, osteoporosis and menopause), more research to clarify the influence of oestrogen on brain injury is urgently required.
Keywords
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Kirsty B. Gordon, I. Mhairi Macrae, Hilary V.O. Carswell,