Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9424388 | Journal of Neuroscience Methods | 2005 | 5 Pages |
Abstract
We previously described a reliable system to control the timing of multiple stimuli and to detect behavioral eyeblink responses in fMRI studies of learning in animals. Here, we report a significant advancement of the original system, which incorporates a fiber-optic probe in order to avoid the interference associated with the application of pulsed field gradients during MR imaging, particularly echo planar imaging. Eyeblink responses recorded with our fiber-optic probe and modified detection circuit demonstrate the ability of our new system to acquire behavioral data free of gradient-induced artifacts, thereby eliminating the need for low-pass filtering. This fiber optic-based system should be applicable to both animal and human imaging experiments.
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Michael J. Miller, Limin Li, Craig Weiss, John F. Disterhoft, Alice M. Wyrwicz,