Sprouting of mossy fibers and presynaptic inhibition by group II metabotropic glutamate receptors in pilocarpine-treated rat hippocampal slice cultures

Article ID	Journal	Published Year	Pages	File Type
9425589	Neuroscience	2005	18 Pages	PDF

Abstract

We provide direct evidence for the development of functional MFS and suggest a novel, axonal mechanism by which presynaptic group II mGluRs can inhibit selected synapses.

Keywords

D-AP-5 fPSP field postsynaptic potential SR95531 mIPSC sEPSC MFS mEPSC mossy fibre sprouting mGluR DNQX TTX NGS aCSF ROD TBS EtOH sIPSC Ethanol Interneuron TRIS buffer phosphate buffer tetrodotoxin relative optical density Tris-buffered saline spontaneous excitatory postsynaptic current miniature inhibitory postsynaptic current Spontaneous inhibitory postsynaptic current miniature excitatory postsynaptic current DIV days in vitro normal goat serum granule cell Cbi lactate dehydrogenase LDH artificial cerebrospinal fluid Metabotropic glutamate receptor

Related Topics

Life Sciences Neuroscience Neuroscience (General)

Sprouting of mossy fibers and presynaptic inhibition by group II metabotropic glutamate receptors in pilocarpine-treated rat hippocampal slice cultures

Authors

A.M. Thomas, A.A. Corona-Morales, F. Ferraguti, M. Capogna,