Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9451191 | Chemosphere | 2005 | 12 Pages |
Abstract
Correlations were observed between dioxin total toxic equivalents (total TEQ) in blood and total TEQ in adipose tissue (r = 0.913, P < 0.0001), breast milk (r = 0.695, P = 0.0007), and cord blood (r = 0.759, P < 0.0001). Dioxin levels transferred to fetuses and nursing infants reflect cumulative maternal concentrations of dioxins. A linear regression equation was introduced to predict total TEQ in breast milk and cord blood from dioxin levels in maternal blood, which should prove useful in evaluating fetal and infant risk of dioxin exposure. Total TEQ in cord blood were approximately 26% lower than in maternal blood (P < 0.0001). The results of this study suggest that transplacental transfer differs depending on the dioxin congener. Total TEQ in breast milk were approximately 30% lower in the Chlorella group than in controls (P = 0.0113). This finding suggests that maternal transfer of dioxins can be reduced using dietary measures such as Chlorella supplements.
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Authors
Shiro Nakano, Taketoshi Noguchi, Hideo Takekoshi, Go Suzuki, Masuo Nakano,