| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9465788 | Marine Pollution Bulletin | 2005 | 5 Pages |
Abstract
The in vitro aryl hydrocarbon receptor (AhR) agonist potency of offshore produced water effluents, collected from the United Kingdom Continental Shelf, was determined using the dioxin responsive (DR)-chemically activated luciferase expression (CALUX) assay. Octadecylsilane (C18) solid phase extraction (SPE) extracts of produced water were exposed to DR-CALUX cells for 24Â h in order to investigate the contribution in potency from compounds that are stable to metabolism by the CALUX cells during exposure. The stable AhR agonist potency determined over 24Â h was highly variable and ranged from 1 to 430Â ng TCDD TEQCALUXÂ lâ1. These data reflect the highly variable composition of produced water discharges from different production fields. It is recommended that further work be performed to characterise the full range of stable dioxin like AhR agonists present in offshore produced water discharges using techniques such as bioassay-directed analysis.
Keywords
Related Topics
Physical Sciences and Engineering
Earth and Planetary Sciences
Oceanography
Authors
Mark R. Hurst, Yin L. Chan-Man, Jan Balaam, John E. Thain, Kevin V. Thomas,