Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9466141 | Marine Pollution Bulletin | 2005 | 7 Pages |
Abstract
In this study, we propose a simple hydrophobicity-based approach to predict the toxicity of mixtures of marine organic micropollutants. Fifty mixtures were chosen, comprising individual chemicals randomly chosen from three halogenated benzenes, three phenols, two petroleum hydrocarbons, three polychlorinated biphenyls (PCBs), four organochlorine pesticides (OCPs) and two herbicides, with the intention of simulating the mixtures of organic micropollutants that may exist in some marine waters. The hydrophobicity of the mixtures was quantified by measuring the C18-EmporeTM disk/water partition coefficients (KMD). A KMD-based approach was proposed to describe their toxicity to Photobacterium phosphoreum, and the application of this approach to another 10 related mixtures proved its predictive capability, as indicated by the consistency between the predicted and observed toxicities (r2Â =Â 0.905, SEÂ =Â 0.101, and FÂ =Â 76.325 at PÂ <Â 0.001). This predictive capability convinces us that the KMD-based approach provides a general approach to predicting the toxicity of mixtures of organic micropollutants in marine water.
Related Topics
Physical Sciences and Engineering
Earth and Planetary Sciences
Oceanography
Authors
Zhifen Lin, Ping Zhong, Xiaojun Niu, Kedong Yin, Hongxia Yu, Jianwei Du,