| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 950621 | Journal of Psychosomatic Research | 2006 | 5 Pages |
ObjectiveTo find differences in heart rate before and after refeeding and to identify which parameters of autonomic activity and endocrine function are associated with these differences.MethodsBefore and after the start of refeeding, body weight, RR interval (RRI), heart rate variability, endocrine function, and energy expenditure were measured in nine female anorexia nervosa patients.ResultsAfter short-term refeeding, mean daytime heart rate rose from 54.9 to 69.4 bpm (P<.05). The changes in sympathetic activity were correlated negatively with the changes in RRI (r=−.933, P<.001). Urine C-peptide, IGF-1, and fT3 increased significantly, and norepinephrine tended to increase.ConclusionWe demonstrated that autonomic nervous activity was relevant to changes in heart rate during refeeding, and it is speculated that the increases in insulin secretion, thyroid function, and IGF-1 were responsible for the mechanisms.
