Generalized arterial calcification of infancy—Findings at post-mortem computed tomography and autopsy

•Generalized arterial calcification in infancy (GACI) is a rare genetic disorder.•GACI is characterized by abnormal vascular calcification and marked myointimal proliferation.•GACI is often fatal due to complications of cardiac ischemia, hypertension and cardiac failure.•Postmortem Computed Tomography demonstrates abnormal vascular and soft tissue calcification.

Generalized arterial calcification in infancy is a rare genetic disorder characterized by abnormal calcification of large and medium sized arteries and marked myointimal proliferation resulting in arterial stenosis. The condition is often fatal secondary to complications of cardiac ischemia, hypertension and cardiac failure. In this report we describe the findings at post mortem computed tomography, histology and autopsy.