| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9557174 | Phytochemistry | 2005 | 5 Pages |
Abstract
Six lignans, including the cyclolignan 3,4â²-dihydroxy-3â²,4-dimethoxy-6,7â²-cyclolignan, were isolated from Larrea tridentata. All of the compounds were assessed for their growth inhibitory activity against human breast cancer, human colon cancer and human melanoma cell lines (IC50 = 5-60 μM). Linear butane-type lignans were most potent.
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Authors
Joshua D. Lambert, Shengmin Sang, Ann Dougherty, Colby G. Caldwell, Ross O. Meyers, Robert T. Dorr, Barbara N. Timmermann,