| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9560615 | Polymer Degradation and Stability | 2005 | 8 Pages |
Abstract
The in vitro degradation behaviour of non-porous ultra-fine poly(glycolic acid)/poly(l-lactic acid) (PGA/PLA) fibres and porous ultra-fine PGA fibres was investigated. The non-porous ultra-fine PGA/PLA fibres were prepared by electrospinning of a PGA/PLA solution in 1,1,1,3,3,3-hexafluoro-2-propanol and the porous ultra-fine PGA fibres were obtained from them via selective removal of PLA with chloroform. Since PLA has a lower degradation rate than PGA, the degradation rates of the ultra-fine PGA/PLA fibres decreased with increasing content of PLA. The porous ultra-fine PGA fibres were degraded in vitro in the order of non-porous PGAÂ >Â P-PGA/PLA(90/10)Â >Â P-PGA/PLA(70/30)Â >Â P-PGA/PLA(50/50)Â >Â P-PGA/PLA(30/70) due to autocatalytic hydrolysis.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Young You, Sung Won Lee, Ji Ho Youk, Byung-Moo Min, Seung Jin Lee, Won Ho Park,