Total synthesis of TT-1 (rasfonin), an α-pyrone-containing natural product from a fungus Trichurus terrophilus

Total synthesis of TT-1 (1=rasfonin), an α-pyrone-containing natural product from a Fungi Imperfecti Trichurus terrophilus was achieved by a stereoselective method in optically active form, which further provided evidence for the whole structure of TT-1 (1) including the absolute stereochemistry.