Article ID Journal Published Year Pages File Type
9563592 Tetrahedron 2005 9 Pages PDF
Abstract
In the presence of Lewis acid TMSOTf, ring-opening reaction of aryl cyclopropyl ketone with arylaldehyde took place under mild conditions to give 2-(2-hydroxyethyl)-1,3-diarylpropenone in good yield through an atom-economic process. Protection of hydroxy group with triethylsilyl group (TES), the corresponding ring-opened product 7 was obtained in high yield with good geometrical selectivity.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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