Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9564320 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
Two syntheses of the title compound 1 are described based on different approaches for installing the oxazole ring moiety. Formation and dehydration of ketoamide (A) was initially used and scaled up on several kilogram scale, then oxazole anion/iminium coupling (B) was developed for a more convergent approach.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Norihiro Ikemoto, Ross A. Miller, Fred J. Fleitz, Jinchu Liu, Daniel E. Petrillo, Joseph F. Leone, Joseph Laquidara, Benjamin Marcune, Sandor Karady, Joseph D. III, Ralph P. Volante,