Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9565083 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
A new and efficient route to a ketolide aglycon served as a basis for the unprecedented 5-O-glyco-modification of ketolide antibiotics. Combined with an effective copper-catalyzed triazole-forming reaction a series of novel and potent ketolide antibiotics were synthesized.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alex Romero, Chang-Hsing Liang, Yu-Hung Chiu, Sulan Yao, Jonathan Duffield, Steven J. Sucheck, Ken Marby, David Rabuka, Po Yee Leung, Youe-Kong Shue, Yoshi Ichikawa, Chan-Kou Hwang,