Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9565100 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
A new strategy for the preparation of one-bead-one-peptide libraries compatible with solid-phase screening and subsequent detachment of the peptide from the resin for sequence determination by MS/MS is described. The method is based on the use of ChemMatrix, a new, fully PEG-based resin, together with 4-hydroxymethylbenzoic acid linker.
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Authors
Silvia A. Camperi, Mariela M. Marani, Nancy B. Iannucci, Simon Côté, Fernando Albericio, Osvaldo Cascone,