Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9567638 | Applied Surface Science | 2005 | 10 Pages |
Abstract
In the detergency field of re-usable medical devices, a special attention is focused on the non conventional transmissible agent called prions which is a proteinaceous infectious agent. Few cleaning procedures are effective against prions and few techniques are available to study cleaning effectiveness with respect to proteins in general. In our study, X-ray photoelectron spectroscopy (XPS) has been used to evaluate the effectiveness of detergent formulations to remove proteins from stainless steel surface soiled with a brain homogenate (BH) from human origin. Our results showed that XPS is a reliable surface analysis technique to study chemical species remaining on surface and substrate properties after cleaning procedures. A semi-quantitative evaluation of the detergency effectiveness could also be performed.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
M. Richard, Th. Le Mogne, A. Perret-Liaudet, G. Rauwel, J. Criquelion, M.I. De Barros, J.C. Cêtre, J.M. Martin,