| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9587316 | Journal of Magnetic Resonance | 2005 | 5 Pages |
Abstract
Two modifications of the triple-resonance CANCO sequence, designed for backbone assignment in proteins [Angew. Chem. Int. Ed. 43 (2004) 2257], are presented here. These two new sequences display the intra-residue Ca-CO correlation selectively, while in the original sequence both the inter- and the intra-residue correlations were present. In addition, one of the two variants benefits from an improved sensitivity. Both sequences are a useful complement to the CANCO sequence for facile sequence-specific protein assignment by protonless NMR.
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Authors
Wolfgang Bermel, Ivano Bertini, Isabella C. Felli, Roberta Pierattelli, Paul R. Vasos,