| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9591355 | Journal of Molecular Structure: THEOCHEM | 2005 | 4 Pages |
Abstract
Based on molecular modeling techniques we constructed a rational 3D model of ORF3 in SARS coronavirus (SARS-CoV). Our studies suggest that the function of ORF3 could be involved in FAD/NAD binding according to its predicted structure and comparison with other structure neighbors. Furthermore, we identified three pairs of non-canonical N-Hâ¯Ï interactions in the structure of ORF3, which can make contributions to the stability of protein structure. These results provide important clues for better understanding of SARS-CoV ORF3 and trying new therapeutic strategies.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Xue Wu Zhang, Yee Leng Yap,