Sex differences in age-related motor slowing in the rhesus monkey: behavioral and neuroimaging data

All monkeys performed similarly in the test with the simplest rod. In the test with complex rods; however, age-related slowing of motor function was evident in males, but not in females. Age-related decreases in the normalized caudate and putamen volumes were similar in males and in females. In addition, motor speed was not significantly correlated to any of the neuroanatomical measures under study. Further studies will be necessary to uncover the neurohormonal bases of the differential age-related motor decline between males and females.