Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9748440 | Journal of Chromatography A | 2005 | 7 Pages |
Abstract
A novel sorbent, dihydroxylated polymethylmethacrylate (DHPMM), coated on hollow-fiber membrane, is used for the polymer-coated hollow-fiber microextraction of trace amounts of natural and synthetic estrogens, such as diethylstilbestrol, estrone, 17β-estradiol and 17α-ethynylestradiol, in aqueous samples. In this procedure, estrogens were extracted using the functionalized polar DHPMM polymer with derivatization using N-methyl-N-(trimethylsilyl)trifluoroacetamide followed by gas chromatography-mass spectrometric analysis. The detection limits for estrogens in aqueous sample were between 0.03 and 0.8 ng lâ1 and the calibration curves were linear over the concentration range 0.05-10 μg lâ1 and had correlation coefficients of >0.994. The relative standard deviations (RSDs) were <15% (n = 3). This simple, accurate, sensitive and selective analytical method is applicable to the determination of trace amounts of estrogens in reservoir and potable water samples.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Chanbasha Basheer, Akhila Jayaraman, Meng Keow Kee, Suresh Valiyaveettil, Hian Kee Lee,