| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9748666 | Journal of Chromatography A | 2005 | 6 Pages |
Abstract
A comparative study of the enantiomeric separation of several antiulcer drugs such as omeprazole, lansoprazole, rabeprazole and pantoprazole using HPLC and supercritical fluid chromatography (SFC) on the Chrialpak AD column is presented in this work. The results show that employing the above mentioned column only two compounds (omeprazole and pantoprazole) could be enantiomerically resolved using HPLC, on the contrary SFC allowed the enantiomeric separation of all the compounds studied with higher resolutions and lower analysis times.
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Authors
L. Toribio, M.J. del Nozal, J.L. Bernal, C. Alonso, J.J. Jiménez,