Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9748702 | Journal of Chromatography A | 2005 | 5 Pages |
Abstract
Several polymethoxylated flavones including nobiletin, 3,5,6,7,8,3â²,4â²-heptamethoxyflavone, tangeretin and 5-hydroxy-6,7,8,3â²,4â²-pentamethoxyflavone were separated from Tangerine peel (Juhong in Chinese) by high-speed counter-current chromatography (HSCCC) with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (1:0.8:1:1, v/v). Then, 26Â mg of nobiletin, 6Â mg of 3,5,6,7,8,3â²,4â²-heptamethoxyflavone, 35Â mg of tangeretin and 11Â mg of 5-hydroxy-6,7,8,3â²,4â²-pentamethoxyflavone could be obtained from 150Â mg crude extracts and their purities were 98.6%, 95.9%, 99.8% and 96.8%, respectively. All these constituents were identified by EI-MS and 1H NMR.
Keywords
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Xiao Wang, Fuwei Li, Hongxia Zhang, Yanling Geng, Jingpeng Yuan, Ting Jiang,