Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9749138 | Journal of Chromatography A | 2005 | 6 Pages |
Abstract
Poly(l-alanine)-grafted porous silica (Sil-Ala22) was prepared by polymerization of N-carboxyanhydride of l-alanine initiated by 3-aminopropylated silica. Its selective interaction with aromatic guest molecules was evaluated by the retention time in liquid chromatography using the column packed with Sil-Ala22. Sil-Ala22 showed a specific selective retention with discriminating molecular shapes, such as molecular length, linearity and planarity. This selectivity can be explained by a multiple Ï-Ï interaction with the carbonyl groups one dimensionally-aligned on the rigid β-form structure in the peptide main chain. Chiral separation with Sil-Ala22 was also described.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Atsuomi Shundo, Toshihiko Sakurai, Makoto Takafuji, Shoji Nagaoka, Hirotaka Ihara,