| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9754413 | Journal of Pharmaceutical and Biomedical Analysis | 2005 | 11 Pages |
Abstract
Form II, metastable and monotropically related to Form I, generates through desolvation of Form III, very often present in industrial processing, where crystallization from ethanol solution is a common practice. For the sake of clarity, the presence of polymorphic forms should be reported in the drug master files of MH. However, since MH is readily water soluble, the observed polymorphism has no relevance to its typical clinical use as aqueous solutions.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
V. Giannellini, M. Bambagiotti-Alberti, G. Bartolucci, B. Bruni, S.A. Coran, F. Costantino, M. Di Vaira,