| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9754424 | Journal of Pharmaceutical and Biomedical Analysis | 2005 | 4 Pages |
Abstract
The gas chromatography (GC) method for enantioseparation of well-known non-steroidal anti-inflammatory drugs ibuprofen, fenoprofen and ketoprofen methyl esters mixture was developed. Best enantioseparation was performed on capillary column with heptakis-(2,3-di-O-methyl-6-O-t-butyldimethyl-silyl)-β-cyclodextrin stationary phase and hydrogen used as a carrier gas. Initial temperature, program rate and carrier pressure were optimized to obtain best resolution between enantiomers.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Marinko PetroviÄ, Željko Debeljak, Nikola BlaževiÄ,