| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9754527 | Journal of Pharmaceutical and Biomedical Analysis | 2005 | 4 Pages |
Abstract
A rapid gravimetric method for determining drug candidate solubility in organic solvents has been developed. The scale, speed, precision, and accuracy of the method make it ideal for solubility screening of pharmaceutical compounds during early development. The method utilizes a thermogravimetric analyzer to automate drying and weighing. Results for model compounds compare favorably with literature values.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Landon R. Greene, Anthony C. Blackburn, Jonathan M. Miller,