Reverse resonance and stochastic resonance in intracellular calcium oscillations

•Reverse resonance exhibits in the function of RCV vs. time delay.•Reverse resonance exhibits in the function of RCV vs. strength of noises as time delay increases.•Both stochastic and reverse resonance are observed in the function of RCV vs. correlation time with varying strength of noises.

The roles of time delay on the coherence resonance are investigated in the intracellular calcium oscillation system described by the processes of active and passive transport of intracellular Ca2+ driven by colored noises. From the numerical simulation of the reciprocal coefficient of variance of interspike intervals of calcium spikes by the method of second-order algorithm, the results indicate that: (i) The stochastic or reverse synchronization is induced by a certain value of time delay or correlation time; (ii) A phenomenon of reverse resonance can be obtained in the function of reciprocal coefficient of variance vs. time delay or vs. strength of noises as time delay increases; (iii) Both stochastic and reverse resonance are observed in the function of reciprocal coefficient of variance vs. correlation time with varying strength of noises.