Article ID Journal Published Year Pages File Type
9757462 Vibrational Spectroscopy 2005 5 Pages PDF
Abstract
In this contribution, we discuss state-of-the-art methodology for the collection and analysis of hyperspectral images of tissue that will become useful in complementing classical histopathology. In particular, we discuss sampling strategies, data collection methods, and computational approaches to produce pseudo-color maps of large tissue sections of lymph nodes, up to about 100 mm2 in size. The latter efforts include methods to reduce the presence of dispersion artifacts in IR transflection micro-spectra which can greatly impact the statistical analyzes performed on the data, such as hierarchical cluster analysis and principal components analysis.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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