| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9757471 | Vibrational Spectroscopy | 2005 | 7 Pages |
Abstract
The objective of the present study was to establish the conditions for infrared spectroscopy of single living cells in cell culture under aqueous media, using a high brilliance synchrotron light source to achieve acceptable S/N at the necessary high spatial resolution. This is experimentally challenging, but brings a number of significant advantages. The data presented show that the infrared spectra of single living cells can be monitored over several hours with high reproducibility, as well as confirming that acquisition of spectral data from single cells can contribute new insights that are not available from measurements of cell populations.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
David A. Moss, Michael Keese, Rainer Pepperkok,