| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9757621 | Chemistry and Physics of Lipids | 2005 | 9 Pages |
Abstract
It has been shown using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and its combination with thin-layer chromatography (TLC) that the action of the ascorbate/Fe2+/H2O2 oxidizing system on cardiolipin and galactocerebroside results in the formation of phosphatidic acid (PA) and ceramide (Cer), respectively. These data, when combined with results obtained on radiolysis of similar substances, allowed the conclusion that the formation of PA and Cer occurs via an OH-induced fragmentation taking place in polar moiety of the starting substrates.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Irina Yurkova, Mikhail Kisel, Juergen Arnhold, Oleg Shadyro,