| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9769244 | European Journal of Medicinal Chemistry | 2005 | 5 Pages |
Abstract
Synthesis, spectroscopic and biological properties of new bis(3-arylimidazolidinyl-1)methanes are described. These compounds were synthesized by condensation reaction between N-arylethylenediamines and formaldehyde. Chemical structures were confirmed by means of their 1H- and 13C-NMR and mass spectroscopic data. Investigation of in vitro antimicrobial activity was performed using Gram-negative and Gram-positive bacteria as well as antifungal studies against Aspergillus niger and Candida albicans. Minimal inhibitory concentrations of active compounds were determined.
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Authors
Isabel Perillo, Evangelina Repetto, MarÃa Cristina Caterina, Rosana Massa, Gabriel Gutkind, Alejandra Salerno,