| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9769269 | European Journal of Medicinal Chemistry | 2005 | 10 Pages |
Abstract
A series of pyrimidyl-5-hydroxamic acids was prepared for evaluation as inhibitors of histone deacetylase (HDAC). Amino-2-pyrimidinyl can be used as a linker to provide HDAC inhibitors of good enzymatic potency.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Patrick Angibaud, Janine Arts, Kristof Van Emelen, Virginie Poncelet, Isabelle Pilatte, Bruno Roux, Sven Van Brandt, Marc Verdonck, Hans De Winter, Peter Ten Holte, Ann Marien, Wim Floren, Boudewijn Janssens, Jacky Van Dun, An Aerts, Jacky Van Gompel,