Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9769273 | European Journal of Medicinal Chemistry | 2005 | 7 Pages |
Abstract
2/3-Arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones 5-9 were synthesized and tested for in vitro antifungal activity against Candida species and Aspergillus niger. The synthesized compounds 5-9 generally showed good activities against Candida albicans and C. tropicalis. The results suggest that the 1,4-naphthoquinones 5-9 would be potent antifungal agents.
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Authors
Chung-Kyu Ryu, Ju-Yeon Shim, Mi Jin Chae, Ik Hwa Choi, Ja-Young Han, Ok-Jai Jung, Jung Yoon Lee, Seong Hee Jeong,