| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9769313 | European Journal of Medicinal Chemistry | 2005 | 6 Pages |
Abstract
The syntheses of substituted piperazinyl pyridyl oxazolidinones 8-16 are described. Their in vitro activities against Gram-positive organisms such as Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus and enterococcus were evaluated by minimum inhibitory concentration (MIC) determination. Compound 8 and 10 were found to be superior to linezolid.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yingjie Cui, Yaxian Dang, Yushe Yang, Shuhua Zhang, Ruyun Ji,