Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
978492 | Physica A: Statistical Mechanics and its Applications | 2006 | 4 Pages |
Abstract
In ontogenetic growth models, the basal metabolic rate is usually assumed to depend on the individual mass following a power law. Here it is shown that, in the case of multicellular tumor spheroids, the emergence of a necrotic core invalidates this assumption. The implications of this result for spheroid growth are discussed, and a procedure to determine the growth parameters using macroscopic measurements is proposed.
Related Topics
Physical Sciences and Engineering
Mathematics
Mathematical Physics
Authors
C.A. Condat, S.A. Menchón,