Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
97987 | Forensic Science International | 2006 | 5 Pages |
Abstract
The applicability of capillary electrophoresis (CE) with a UV detector using highly sulfated γ-cyclodextrin as a chiral selector was examined for analysis of impurities in seized methamphetamine. Samples of methamphetamine-hydrochloride dissolved in water at a high concentration (20 mg/mL) were analyzed. Electrokinetic injection has an advantage over hydrodynamic injection for improving the detection of trace impurities. Small peaks of the precursor impurities, such as (1R,2S)-(−)-ephedrine and (1S,2S)-(+)-pseudoephedrine, were detected and quantified without extraction. The seized drugs could be classified into three groups based on the contents of the two impurities.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yuko T. Iwata, Hiroyuki Inoue, Kenji Kuwayama, Tatsuyuki Kanamori, Kenji Tsujikawa, Hajime Miyaguchi, Tohru Kishi,