Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9801445 | Science and Technology of Advanced Materials | 2005 | 6 Pages |
Abstract
A novel sponge composed of a poly (lactic acid) composite skeleton covered with bonelike apatite (b-HA) was produced via a particle-leaching technique combined with a biomimetic processing. The sponge has a large porosity of â¼75% with large-sized pores and shows mechanical ductility. After incubation of human osteoblasts for 7 days, numerous cells attached to the surface of the skeleton, which was covered with b-HA. One result of the osteoclastic cell culture showed that the b-HA on the composite has excellent bioresorbability. The sponge is expected to be one of the promising candidates for bone tissue engineering scaffolds.
Related Topics
Physical Sciences and Engineering
Materials Science
Materials Science (General)
Authors
Hirotaka Maeda, Toshihiro Kasuga, Masayuki Nogami, Minoru Ueda,