| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9818198 | Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms | 2005 | 6 Pages |
Abstract
This study involves the analysis of human NPC xenograft tumors in murine models using the National University of Singapore nuclear microscope. PDT was carried out using the photosensitiser hypericin under various conditions. The microbeam techniques of particle induced X-ray emission, Rutherford backscattering spectrometry and scanning transmission ion microscopy were used to quantify elemental concentrations in cryo-fixed sections of tumor tissue. Preliminary results are presented as well as their implications for the mechanisms underlying photodynamic cell killing.
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Authors
P.S.P. Thong, F. Watt, M.Q. Ren, K.C. Soo, M. Olivo,