| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 98405 | Forensic Science International | 2006 | 7 Pages |
Abstract
We report triallelic patterns in several short tandem repeat (STR) loci revealed by routine paternity testing using the commercial AMPFlSTR®Profiler™ and AMPFlSTR®SGMplus™ kits. One case where the TPOX-locus (2p25.3) produced three peaks from the blood sample of a child was analysed further. Quantitative polymerase chain reaction (QPCR) and STR typing of the DNAs of the family trio revealed a large (>1.59 Mb) duplication flanking the TPOX-locus in chromosome 2 in both the mother and child. The implications of such genetic anomalies for paternity testing are discussed.
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Matti Lukka, Gunnar Tasa, Pekka Ellonen, Kirsi Moilanen, Vitali Vassiljev, Ismo Ulmanen,