Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9871635 | Applied Radiation and Isotopes | 2005 | 11 Pages |
Abstract
The production of no-carrier-added (NCA) α-emitter 211At/211gPo radionuclides for high-LET targeted radiotherapy and immunoradiotherapy, through the 209Bi(α,2n) reaction, together with the required wet radiochemistry and radioanalytical quality controls carried out at LASA is described, through dedicated irradiation experiments at the MC-40 cyclotron of JRC-Ispra. The amount of both the γ-emitter 210At and its long half-lived α-emitting daughter 210Po is optimised and minimised by appropriate choice of energy and energy loss of α particle beam. The measured excitation functions for production of the main radioisotopic impurity 210Atâ210Po are compared with theoretical predictions from model calculations performed at ENEA.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
F. Groppi, M.L. Bonardi, C. Birattari, E. Menapace, K. Abbas, U. Holzwarth, A. Alfarano, S. Morzenti, C. Zona, Z.B. Alfassi,