Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9872075 | International Journal of Radiation Oncology*Biology*Physics | 2005 | 7 Pages |
Abstract
Conclusions: While mastectomy is considered the standard surgical salvage of IBTR, SBCS is feasible and prognostic factors are related to favorable tumor biology and early detection. Patients with BRCA1/2 germline mutations may be less appropriate for SBCS, as multicentric disease was more prevalent. Patients who underwent SBCS had comparable outcomes as those who underwent SM, but remain at continued risk for IBTR. A prospective trial evaluating repeat lumpectomy and partial breast reirradiation is discussed.
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Authors
Tracy E. M.D., Henry M. M.D., Douglas W. M.D., Donald R. M.D., Bruce G. M.D.,