Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9872163 | International Journal of Radiation Oncology*Biology*Physics | 2005 | 9 Pages |
Abstract
Conclusions: High doses (79.2 Gy) were safely delivered in selected patients by our adaptive radiotherapy process. Under the rectal dose-volume histogram constraints for the dose level selection, the risk of chronic rectal toxicity is similar among patients treated to different dose levels. Therefore, rectal chronic toxicity rates reflect the dose-volume cutoff used and are independent of the actual dose levels. On the other hand, a larger PTV will increase the rectal wall dose and chronic rectal toxicity rates. PTV volume and dose constraints should be defined, considering their potential benefit.
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Authors
Carlos (F.A.C.R.), Di D.Sc., Larry L. M.D., Daniel M.D., David M. D.Sc., Donald S. M.D., Alvaro A. M.D.,